Validación del EDACS Score para la predicción del SCA y MACE en el servicio de urgencias de una clínica de Barranquilla-Colombia
| dc.contributor.advisor | Ortega Ramírez, Gustavo Andrés | |
| dc.contributor.advisor | Ardila Pereira, Laura Cecilia | |
| dc.contributor.author | Romero Jiménez, Evasandrid | |
| dc.contributor.author | León Cifuentes, Reiner | |
| dc.coverage.spatial | Barranquilla | spa |
| dc.creator.email | reynerleon@hotmail.com | spa |
| dc.creator.email | reiner-leonc@unilibre.edu.co | spa |
| dc.creator.email | evasandrid-romeroj@unilibre.edu.co | spa |
| dc.date.accessioned | 2024-07-26T21:03:25Z | |
| dc.date.available | 2024-07-26T21:03:25Z | |
| dc.date.created | 2024-06 | |
| dc.description.abstract | Introducción: En el mundo, incluyendo nuestra población, las enfermedades cardiovasculares siguen siendo la principal causa de muerte, la creación de escalas ha permitido realizar diagnósticos precoces que conllevan a tratamientos oportunos, por lo que queremos validar una escala clínica diagnóstica para esta enfermedad en nuestra población. Objetivo: Validar el Emergency Department assessment Chest Pain Score (EDACS) en la población de la ciudad de Barranquilla. Metodología: Se realizó un estudio de cohorte con 189 pacientes mayores a 18 años que consultaron al servicio de urgencias con dolor torácico de aparición menor a 24 horas con seguimiento durante 30 días del evento índice; los datos fueron tomados de historias clínicas de los pacientes de la Clínica General del Norte en Barranquilla, en el período 2023. Resultados: La población elegible final consistió en 189 pacientes seleccionados entre un total de 1543, quienes tenían historias clínicas completas y cumplían con todos los criterios de inclusión. En cuanto a la escala EDACS, los pacientes que presentaron MACE obtuvieron una puntuación promedio significativamente mayor (17.37 ± 5.43) en comparación con los pacientes sin MACE (14.18 ± 5.69) (p=0.0049). Se determinó que 14 es el punto de corte para la población colombiana, y la razón de probabilidades fue de 3.36, lo que sugiere que los pacientes con una puntuación EDACS de 14 o más tienen 3.36 veces más probabilidades de experimentar un MACE en comparación con aquellos con una puntuación menor a 14. Esta asociación también fue estadísticamente significativa (p=0.004), con un intervalo de confianza del 95% de 1.45 a 7.75. Conclusiones: La validación del EDACS score en nuestra población demuestra su alta sensibilidad para predecir MACE, reafirmando su utilidad clínica en el manejo del dolor torácico en el servicio de urgencias. | spa |
| dc.description.abstractenglish | Background: In the world, including our population, cardiovascular diseases remain the leading cause of death, the creation of scales has allowed early diagnoses that lead to timely treatments, so we want to validate a clinical diagnostic scale for this disease in our population. Objective: To validate the EDACS score in our population. Methodology: A cohort study was conducted with 189 patients over 18 years of age consulting the emergency department with chest pain of onset < 24 h with follow-up for 30 days of the index event; data were taken from medical records patients at the Clínica General del Norte in Barranquilla, in the period 2023. Results: The final eligible population consisted of 189 patients out of 1543, with complete medical records and who met all inclusion criteria. On the EDACS scale, patients with MACE had a significantly higher mean score (17.37 ± 5.43) compared to patients without MACE (14.18 ± 5.69) (p=0.0049). 14 is considered the Colombian cut-off point, the odds ratio was 3.36, suggesting that patients with an EDACS score of 14 or more are 3.36 times more likely to experience a MACE compared to those with a score less than 14. This association was also statistically significant (p=0.004), with a 95% confidence interval of 1.45 to 7.75. Conclusions: The validation of the EDACS score in our population demonstrates its high sensitivity to predict MACE, reaffirming its clinical usefulness in the management of chest pain in the emergency department. | spa |
| dc.description.sponsorship | Universidad Libre Seccional Barranquilla -- Facultad de Ciencias de la Salud y Exactas y Naturales -- Especialización en Medicina Interna | spa |
| dc.format | spa | |
| dc.identifier.uri | https://hdl.handle.net/10901/29574 | |
| dc.relation.references | Makki N, Brennan TM, Girotra S. Acute coronary syndrome. J Intensive Care Med. 2015;30(4):186–200. | spa |
| dc.relation.references | Thygesen K, Alpert JS, Jaffe AS, Chaitman BR, Bax JJ, Morrow DA, et al. Fourth Universal Definition of Myocardial Infarction (2018). Circulation [Internet]. 2018 Nov 13;138(20):e618–51. Available from: https://doi.org/10.1161/CIR.0000000000000617 | spa |
| dc.relation.references | Ralapanawa U, Sivakanesan R. Epidemiology and the Magnitude of Coronary Artery Disease and Acute Coronary Syndrome: A Narrative Review. J Epidemiol Glob Health [Internet]. 2021;11(2):169. Available from: https://www.atlantis-press.com/article/125950929 | spa |
| dc.relation.references | Rodriguez Arciniegas CT, Betancur Romero JE, Porras Ramirez A. INFARTO AGUDO DE MIOCARDIO EN COLOMBIA (2011 – 2021), UN ESTUDIO DE CARGA DE LA ENFERMEDAD. Universidad del Bosque. 2023. | spa |
| dc.relation.references | Bhatt DL, Lopes RD, Harrington RA. Diagnosis and Treatment of Acute Coronary Syndromes: A Review. Jama [Internet]. 2022;327(7):662–75. Available from: http://gestoreditorial.resed.es/DOI/PDF/ArticuloDOI_3571.pdf | spa |
| dc.relation.references | Gulati M, Levy PD, Mukherjee D, Amsterdam E, Bhatt DL, Birtcher KK, et al. 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/ SCMR Guideline for the Evaluation and Diagnosis of Chest Pain: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Vol. 144, Circulation. 2021. 368–454 p. | spa |
| dc.relation.references | Stepinska J, Lettino M, Ahrens I, Bueno H, Garcia-Castrillo L, Khoury A, et al. Diagnosis and risk stratification of chest pain patients in the emergency department: focus on acute coronary syndromes. A position paper of the Acute Cardiovascular Care Association. Eur Hear J Acute Cardiovasc Care. 2020;9(1):76–89. | spa |
| dc.relation.references | Gaviria S, Ramírez A, Alzate M, Contreras H, Jaramillo N, Muñoz MC. Epidemiología del síndrome coronario agudo. Med UPB [Internet]. 2020;39(1):49–56. Available from: https://revistas.upb.edu.co/index.php/medicina/article/view/406 | spa |
| dc.relation.references | Libby P, Pasterkamp G, Crea F, Jang IK. Reassessing the Mechanisms of Acute Coronary Syndromes. Circ Res [Internet]. 2019 Jan 4 [cited 2023 Jul 24];124(1):150–60. Available from: https://pubmed-ncbi-nlm-nih-gov.udea.lookproxy.com/30605419/ | spa |
| dc.relation.references | Anderson JL, Morrow DA. Acute Myocardial Infarction. Campion EW, editor. N Engl J Med [Internet]. 2017 May 25;376(21):2053–64. Available from: http://www.nejm.org/doi/10.1056/NEJMra1606915 | spa |
| dc.relation.references | Than M, Flaws D, Sanders S, Doust J, Glasziou P, Kline J, et al. Development and validation of the emergency department assessment of chest pain score and 2h accelerated diagnostic protocol. EMA Emerg Med Australas [Internet]. 2014 Feb;26(1):34–44. Available from: https://onlinelibrary.wiley.com/doi/10.1111/1742-6723.12164 | spa |
| dc.relation.references | Chang AM, Fischman DL, Hollander JE. Evaluation of Chest Pain and Acute Coronary Syndromes. Cardiol Clin [Internet]. 2018;36(1):1–12. Available from: https://doi.org/10.1016/j.ccl.2017.08.001 | spa |
| dc.relation.references | Romero M, Vásquez E, Acero G, Huérfano L. Estimation of the direct costs of coronary events in Colombia. Rev Colomb Cardiol. 2018;25(6):373–9. | spa |
| dc.relation.references | Barstow C, Rice M, McDivitt JD. Acute coronary syndrome: Diagnostic evaluation. Am Fam Physician. 2017;95(3):170–7. | spa |
| dc.relation.references | Bergmark BA, Mathenge N, Merlini PA, Lawrence-Wright MB, Giugliano RP. Acute coronary syndromes. Lancet [Internet]. 2022 Apr;399(10332):1347–58. Available from: http://www.ncbi.nlm.nih.gov/pubmed/32305286 | spa |
| dc.relation.references | Libby P, Pasterkamp G, Crea F, Jang IK. Reassessing the Mechanisms of Acute Coronary Syndromes: The “vulnerable Plaque” and Superficial Erosion. Circ Res. 2019;124(1):150–60. | spa |
| dc.relation.references | Thygesen K, Alpert JS, Jaffe AS, Simoons ML, Chaitman BR, White HD. Third universal definition of myocardial infarction. J Am Coll Cardiol. 2012 Oct 16;60(16):1581–98. | spa |
| dc.relation.references | Isaza-Jaramillo S, Jaimes-Barragán F. Ronda clínica y epidemiológica: aproximación a los modelos de predicción clínica . Vol. 30, Iatreia . scieloco ; 2017. p. 92–9. | spa |
| dc.relation.references | Karzulovic L, García P, Wozniak A, Villarroel L, Hirsch T, Concha I, et al. Una regla de predicción clínica ¿anticipa el diagnóstico de la faringitis estreptocóccica en niños de 2 a 15 años? . Vol. 35, Revista chilena de infectología . scielocl ; 2018. p. 476–82. | spa |
| dc.relation.references | Boyle RSJJ, Body R. The Diagnostic Accuracy of the Emergency Department Assessment of Chest Pain (EDACS) Score: A Systematic Review and Meta-analysis. Ann Emerg Med [Internet]. 2021;77(4):433–41. | spa |
| dc.relation.references | Flaws D, Than M, FX S, Christenson J, Boychuk B, JH G, et al. External validation of the emergency department assessment of chest pain score accelerated diagnostic pathway (EDACS-ADP). Emerg Med J [Internet]. 2016;33(9):618–25. | spa |
| dc.relation.references | Aldous S, Pickering J, Richards M, Troughton R, Cullen L, Than M. Comparison of Five Accelerated Diagnostic Protocols for Stratification of Patients Presenting with Acute Chest Pain. Hear Lung Circ [Internet]. 2017;26:S15. | spa |
| dc.relation.references | Chapman AR, Hesse K, Andrews J, Ken Lee K, Anand A, Shah AS V., et al. High-Sensitivity Cardiac Troponin I and Clinical Risk Scores in Patients With Suspected Acute Coronary Syndrome. Circulation [Internet]. 2018 Oct 16;138(16):1654–65. | spa |
| dc.relation.references | Body R, Morris N, Reynard C, PO C. Comparison of four decision aids for the early diagnosis of acute coronary syndromes in the emergency department. [Internet]. Vol. 37, Emergency medicine journal : EMJ. England; 2020. p. 8–13. Available from: https://pubmed.ncbi.nlm.nih.gov/31767674/ | spa |
| dc.relation.references | Hrečko J, Pudil R, Dokoupil J, Pařízek P. COMPARISON of SIX DECISION AID RULES for DIAGNOSIS of ACUTE MYOCARDIAL INFARCTION in ELDERLY PATIENTS PRESENTING to the EMERGENCY DEPARTMENT with ACUTE CHEST PAIN. Cor Vasa [Internet]. 2023;65(1):151. Available from: https://www.embase.com/search/results?subaction=viewrecord&id=L640936777&from=export U2 - L640936777 | spa |
| dc.relation.references | Stopyra J, AC S, Hiestand B, BJ W, KM L, Herrington D, et al. Comparison of accelerated diagnostic pathways for acute chest pain risk stratification. [Internet]. Vol. 106, Heart (British Cardiac Society). England; 2020. p. 977–84. Available from: https://pubmed.ncbi.nlm.nih.gov/32269131/ | spa |
| dc.relation.references | Yang SM, Chan CH, Chan TN. HEART pathway and Emergency Department Assessment of Chest Pain Score–Accelerated Diagnostic Protocol application in a local emergency department of Hong Kong: An external prospective validation study. Hong Kong J Emerg Med [Internet]. 2020;27(1):30–8. Available from: https://www.embase.com/search/results?subaction=viewrecord&id=L625545280&from=export U2 - L625545280 | spa |
| dc.relation.references | Mark DG, Huang J, Kene M V., Sax DR, Cotton DM, Lin JS, et al. Prospective Validation and Comparative Analysis of Coronary Risk Stratification Strategies Among Emergency Department Patients With Chest Pain. J Am Heart Assoc [Internet]. 2021 Apr 6;10(7). Available from: https://www.embase.com/search/results?subaction=viewrecord&id=L2006979558&from=export U2 - L2006979558 | spa |
| dc.relation.references | Valdivia M, Stolz U, Fermann GJ. Performance of history, ECG, age, risk factors, troponin score vs emergency department assessment of chest pain score among patients with a cardiac evaluation in the emergency department. Acad Emerg Med [Internet]. 2021;28:S199. Available from: https://www.embase.com/search/results?subaction=viewrecord&id=L635076630&from=export U2 - L635076630 | spa |
| dc.relation.references | Chae B, Ahn S, Ryoo SM, Kim Y-JJ, Seo D-WW, Sohn CH, et al. Performance analysis considering endpoints for three accelerated diagnostic protocols for chest pain. Am J Emerg Med [Internet]. 2023 Feb;64:51–6. Available from: https://www.embase.com/search/results?subaction=viewrecord&id=L2021329217&from=export U2 - L2021329217 | spa |
| dc.relation.references | Ng ALY, Yeo CHX, Ong ST, Chua CLY, Liwanagan MG, Lim KK, et al. Improving triage accuracy through a modified nurse-administered emergency department assessment of chest pain score on patients with chest pain at triage (EDACT): A prospective observational study. Int Emerg Nurs [Internet]. 2022 Mar;61:101130. Available from: https://www.embase.com/search/results?subaction=viewrecord&id=L637121491&from=export U2 - L637121491 | spa |
| dc.relation.references | Zaboli A, Ausserhofer D, Sibilio S, Toccolini E, Bonora A, Giudiceandrea A, et al. Effect of the Emergency Department Assessment of Chest Pain Score on the Triage Performance in Patients With Chest Pain. Am J Cardiol [Internet]. 2021;161:12–8. Available from: https://www.embase.com/search/results?subaction=viewrecord&id=L2015036947&from=export U2 - L2015036947 | spa |
| dc.relation.references | Rodrigues FB, Machado M, Santos BDR, Bruetto R, De Souza AM, Maia LN, et al. COMPARISON OF THE RISK SCORES FOR DIAGNOSIS OF ACUTE CORONARY SYNDROMES IN PATIENTS WITH CHEST PAIN IN THE EMERGENCY ROOM. J Am Coll Cardiol [Internet]. 2023 Mar;81(8):1192. Available from: https://www.embase.com/search/results?subaction=viewrecord&id=L2023032045&from=export U2 - L2023032045 | spa |
| dc.relation.references | Gaviria Uribe Al, Rios Muñoz JN, COLOMBIA PDLR DE, COLOMBIA MDSYPS DE. Decreto 1507 de 2014 [Internet]. Colombia; Aug 12, 2014 p. 200. Available from: https://www.minsalud.gov.co/sites/rid/Lists/BibliotecaDigital/RIDE/DE/DIJ/Decreto-1507-DE-2014.pdf | spa |
| dc.relation.references | Gaviria Uribe Al, Rios Muñoz JN, COLOMBIA PDLR DE, COLOMBIA MDSYPS DE. Decreto 1477 de 2014 [Internet]. Colombia; Aug 5, 2014 p. 109. Available from: https://www.mintrabajo.gov.co/documents/20147/36482/decreto_1477_del_5_de_agosto_de_2014.pdf/b526be63-28ee-8a0d-9014-8b5d7b299500 | spa |
| dc.relation.references | Than M, Flaws D. Emergency Department Assessment of Chest Pain Score (EDACS) [Internet]. MDCalc. 2023. Available from: https://www.mdcalc.com/calc/1858/emergency-department-assessment-chest-pain-score-edacs | spa |
| dc.relation.references | About RStudio [Internet]. 2021. Available from: https://www.rstudio.com/about | spa |
| dc.relation.references | Demostehes, K. Gersh, B. Camm, A. A Clinical Perspective on Sudden Cardiac Death. Arrhythmia & Electrophysiology Review 2016;5(3):177–82. https://doi.org/10.15420/aer.2016:11:2 | spa |
| dc.relation.references | Andersen LW, Holmberg MJ, Berg KM, Donnino MW, Granfeldt A. In-Hospital Cardiac Arrest: A Review. JAMA. 2019 Mar 26;321(12):1200-1210. doi: 10.1001/jama.2019.1696. | spa |
| dc.relation.references | Samsky MD, Morrow DA, Proudfoot AG, Hochman JS, Thiele H, Rao SV. Cardiogenic Shock After Acute Myocardial Infarction: A Review. JAMA. 2021;326(18):1840–1850. doi:10.1001/jama.2021.18323 | spa |
| dc.relation.references | Tehrani B, Truesdell A, Psotka M, et al. A Standardized and Comprehensive Approach to the Management of Cardiogenic Shock. J Am Coll Cardiol HF. 2020 Nov, 8 (11) 879–891. https://doi.org/10.1016/j.jchf.2020.09.005 | spa |
| dc.relation.references | 42. Dahal, T., Tamang, A., Shrestha, R., Rai, A., Tripathee, S. (2023). Efficacy of Chest Pain Severity and Clinical Assessment in an Emergency Department: A Quantitative Retrospective Study of 1200 Patients. IAR Journal of Clinical Research. | spa |
| dc.relation.references | 43. Aldous, S., Richards, A. M., Cullen, L., Troughton, R., Than, M. (2017). The EDACS-ADP Identifies Patients with Chest Pain Who Are at Very Low Risk of Acute Coronary Syndrome in the ED. Annals of Emergency Medicine, 70(5), 737-745. | spa |
| dc.relation.references | Chapman, A. R., Adamson, P. D., Shah, A. S., Anand, A., Strachan, F. E., Ferry, A. V., ... & Mills, N. L. (2018). High-Sensitivity Cardiac Troponin and the Universal Definition of Myocardial Infarction. Circulation, 137(22), 2154-2164 | spa |
| dc.relation.references | 45. Dahal, T., Tamang, A., Shrestha, R., Rai, A., Tripathee, S. (2023). Efficacy of Chest Pain Severity and Clinical Assessment in an Emergency Department: A Quantitative Retrospective Study of 1200 Patients. IAR Journal of Clinical Research. | spa |
| dc.relation.references | 46. Aldous, S., Richards, A. M., Cullen, L., Troughton, R., Than, M. (2017). The EDACS-ADP Identifies Patients with Chest Pain Who Are at Very Low Risk of Acute Coronary Syndrome in the ED. Annals of Emergency Medicine, 70(5), 737-745. | spa |
| dc.relation.references | 47. Chapman, A. R., Adamson, P. D., Shah, A. S., Anand, A., Strachan, F. E., Ferry, A. V., ... & Mills, N. L. (2018). High-Sensitivity Cardiac Troponin and the Universal Definition of Myocardial Infarction. Circulation, 137(22), 2154-2164 | spa |
| dc.relation.references | 48. Zaboli, A., Ramezani, J., Jafarzadeh, S., Ramezani, M. (2022). Evaluation of EDACS Score Performance in an Italian Emergency Department: A Retrospective Study. Emergency Medicine Journal, 39(1), 55-60. | spa |
| dc.relation.references | 49. Neumann, J. T., Sörensen, N. A., Rübsamen, N., Ojeda, F., Renne, T., Krämer, B. K., ... & Blankenberg, S. (2018). Discrimination of Patients with Type 2 Myocardial Infarction and Acute Nonischemic Myocardial Injury. Circulation, 138(10), 1036-1045. | spa |
| dc.relation.references | 50. Body, R., Dixon, D., Burrows, G., Pemberton, R., Carley, S., & Mackway-Jones, K. (2017). The Manchester Acute Coronary Syndromes (MACS) Decision Rule: Validation with a New Automated Assay for Heart-Type Fatty Acid-Binding Protein. Emergency Medicine Journal, 34(3), 171-176 | spa |
| dc.relation.references | Congreso de Colombia. Ley 100 de 1993. Por la cual se crea el sistema de seguridad social integral y se dictan otras disposiciones: Diario Oficial No. 41.148, 23 de diciembre de 1993. | spa |
| dc.relation.references | Congreso de Colombia. Ley 1751 de 2015. Por medio de la cual se regula el derecho fundamental a la salud y se dictan otras disposiciones: Diario Oficial No. 49.427, 16 de febrero de 2015. | spa |
| dc.rights.accessrights | info:eu-repo/semantics/openAccess | spa |
| dc.rights.coar | http://purl.org/coar/access_right/c_abf2 | spa |
| dc.rights.license | Atribución-NoComercial-SinDerivadas 2.5 Colombia | spa |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/2.5/co/ | spa |
| dc.subject | Síndrome coronario agudo | spa |
| dc.subject | Dolor en el pecho | spa |
| dc.subject | Métodos diagnósticos | spa |
| dc.subject | Servicios de emergencia | spa |
| dc.subject | Angina inestable | spa |
| dc.subject | Evaluación de riesgos | spa |
| dc.subject | Infarto del miocardio | spa |
| dc.subject.lemb | Angina de pecho | spa |
| dc.subject.lemb | Infarto del miocardio - diagnóstico | spa |
| dc.subject.lemb | Angina inestable | spa |
| dc.subject.lemb | Dolor en el pecho | spa |
| dc.subject.lemb | Urgencias médicas | spa |
| dc.subject.subjectenglish | Acute coronary syndrome | spa |
| dc.subject.subjectenglish | Chest pain | spa |
| dc.subject.subjectenglish | Diagnostic methods | spa |
| dc.subject.subjectenglish | Emergency department | spa |
| dc.subject.subjectenglish | Unstable angina | spa |
| dc.subject.subjectenglish | Risk assessment | spa |
| dc.subject.subjectenglish | Myocardial infarction | spa |
| dc.title | Validación del EDACS Score para la predicción del SCA y MACE en el servicio de urgencias de una clínica de Barranquilla-Colombia | spa |
| dc.title.alternative | Validation of the EDACS Score for the prediction of ACS and MACE in the emergency department of a clinic in Barranquilla-Colombia | spa |
| dc.type.coar | http://purl.org/coar/resource_type/c_7a1f | spa |
| dc.type.driver | info:eu-repo/semantics/bachelorThesis | spa |
| dc.type.hasversion | info:eu-repo/semantics/acceptedVersion | spa |
| dc.type.local | Tesis de Especialización | spa |
Archivos
Bloque original
1 - 2 de 2
Cargando...
- Nombre:
- ROMERO
- Tamaño:
- 2.06 MB
- Formato:
- Adobe Portable Document Format
- Descripción:
- Archivo del trabajo de grado para descargar
Cargando...
- Nombre:
- FORMULARIO AUTORIZACIÓN.pdf
- Tamaño:
- 10.92 MB
- Formato:
- Adobe Portable Document Format
- Descripción:
- Autorización para la publicación
Bloque de licencias
1 - 1 de 1
Cargando...
- Nombre:
- license.txt
- Tamaño:
- 1.71 KB
- Formato:
- Item-specific license agreed upon to submission
- Descripción:
