Perspectivas metagenómicas y taxonómicas de poblaciones metilótrofas del Golfo de México
| dc.contributor.advisor | Tito David, Peña Montenegro | |
| dc.contributor.advisor | Juan David, Sanchez Calderón | |
| dc.contributor.author | Guzmán Viloria, Fabio Andrés | |
| dc.coverage.spatial | Barranquilla | spa |
| dc.creator.email | fabioguzmanv3@gmail.com | spa |
| dc.date.accessioned | 2025-07-17T15:44:00Z | |
| dc.date.available | 2025-07-17T15:44:00Z | |
| dc.date.created | 2024-11-27 | |
| dc.description.abstract | El creciente aumento en la temperatura a nivel global ha hecho que se tengan que buscar alternativas sostenibles para poder mitigar el impacto de los gases de efecto invernadero. El metano es conocido por ser el segundo gas de efecto invernadero con mayor impacto a nivel global, además, se encuentra categorizado como uno de los llamados compuestos C1. Dichos compuestos son de difícil asimilación y utilización por microorganismos que no cuenten con las enzimas necesarias. Afortunadamente, existe un grupo de microorganismos conocidos como metilótrofos, capaces de utilizar compuestos carentes de enlaces carbono-carbono (C1). Sin embargo, su estudio se ha visto comprometido por su dificultad a la hora de ser aislados. En la presente tesis se ensamblaron genomas con la finalidad de reportar microorganismos metilótrofos en el Golfo de México, un ambiente con alta concentración de compuestos C1. Adicionalmente, se consolidó una base de datos con genes marcadores de microorganismos en contextos extremos y un diccionario de vocabulario restringido para la notación taxonómica de genomas ensamblados de metagenomas (MAGs). Finalmente, fueron obtenidos un diccionario de notación taxonómica con lenguaje restringido, una base de datos curada de genes marcadores y MAGs de microorganismos del Golfo de México, se destaca un grupo que podría ser indicativo de actividad metilótrofa. | spa |
| dc.description.abstractenglish | Global temperature increase has led to the need to find sustainable alternatives to mitigate the impact generated by greenhouse gas emissions. Methane is known as the second greenhouse gas with greatest impact globally, moreover, is categorized as one of the so-called C1 compounds. These compounds are difficult to use by microorganisms that do not have the necessary enzymes. Nevertheless, there is a group of microorganisms known as methylotrophs, capable of using compounds lacking carbon-carbon bounds as their sole carbon source. However, their study has been hindered by the challenges associated with their isolation. In this thesis, genomes were assembled with the aim of identifying methylotrophic microorganisms in the Gulf of Mexico, an environmental with high levels of C1 compounds. Additionally, a curated database of maker genes from microorganisms in extreme environments was developed, along with a dictionary for taxonomic annotation of metagenome-assembled genomes (MAGs). Finally, this research obtained a restricted language dictionary for taxonomic annotation, a curated database of marker genes and MAGs of microorganisms from the Gulf of Mexico, highlighting a group that could be a hint of methylotrophic activity. | spa |
| dc.description.sponsorship | Universidad Libre - Facultad de Ciencias de la Salud, Exactas y Naturales - Programa de Microbiología | spa |
| dc.format | spa | |
| dc.identifier.uri | https://hdl.handle.net/10901/31522 | |
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| dc.rights.accessrights | info:eu-repo/semantics/openAccess | spa |
| dc.rights.coar | http://purl.org/coar/access_right/c_abf2 | spa |
| dc.rights.license | Atribución-NoComercial-SinDerivadas 2.5 Colombia | spa |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/2.5/co/ | spa |
| dc.subject | Metagenómas | spa |
| dc.subject | Metilótrofos | spa |
| dc.subject | Genomas ensamblados de metagenomas | spa |
| dc.subject.lemb | Perspectivas metagenómicas y taxonómicas de poblaciones metilótrofas del Golfo de México | spa |
| dc.subject.subjectenglish | Metagenomes | spa |
| dc.subject.subjectenglish | Methylotrophs | spa |
| dc.subject.subjectenglish | Metagenome-assembled genomes | spa |
| dc.title | Perspectivas metagenómicas y taxonómicas de poblaciones metilótrofas del Golfo de México | spa |
| dc.type.coar | http://purl.org/coar/resource_type/c_7a1f | spa |
| dc.type.driver | info:eu-repo/semantics/bachelorThesis | spa |
| dc.type.hasversion | info:eu-repo/semantics/acceptedVersion | spa |
| dc.type.local | Tesis de Pregrado | spa |
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