Revisión exploratoria de la composición fitoquímica y las actividades biológicas asociadas de varias especies del género caulerpa y su potencial en la industria farmacéutica

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dc.contributor.advisorTapia Larios, Claudia Milena
dc.contributor.authorRodríguez Redondo, Maryluna
dc.contributor.authorGuerra Díaz, Romario De Souza
dc.coverage.spatialBarranquillaspa
dc.creator.emailmaryluna-rodriguezr@unilibre.edu.cospa
dc.creator.emailromariod-guerrad@unilibre.edu.cospa
dc.date.accessioned2025-06-26T21:14:17Z
dc.date.available2025-06-26T21:14:17Z
dc.date.created2022
dc.description.abstractEn la actualidad, gran parte de los medicamentos se obtienen a partir de compuestos aislados de seres vivos. Ante esta perspectiva, existe un interés creciente en la búsqueda de nuevos compuestos bioactivos, especialmente en organismos que han sido poco explora-dos hasta ahora, como es el caso de algunas especies de algas marinas. Este trabajo pretendió caracterizar fitoquímicamente e identificar las aplicaciones y beneficios procedentes de los metabolitos secundarios del género Caulerpa. Para llevar a cabo este estudio, Se realizó una revisión exploratoria con enfoque sistemático de artículos científicos en las bases de datos Scopus, PubMed, Marine Drugs, Scielo y Lilacs. El análisis de la información recopilada fue apoyado por el programa Microsoft Excel® y el gestor bibliográfico Zotero®. Se identificó el potencial bio prospectivo de las actividades biológicas de compuestos asociados a especies del género Caulerpa y su impacto en la industria farmacéutica a través de la revisión de 93 artículos científicos. Los hallazgos resaltan la importancia composicional y funcional de los polisacáridos sulfatados, los metabolitos secundarios Caulerpenina y Caulerpina, así como los ácidos grasos y extractos de Caulerpa, debido a que han revelado diversas actividades biológicas, incluyendo el potencial antiinflamatorio, antimicrobiano, antitumoral y antioxidante. La presencia de especies del género Caulerpa en el Caribe colombiano, respaldada por datos de caracterización de diversidad algal a nivel nacional, sugiere un potencial significativo de los recursos subvalorados de Caulerpa en Colombia para su desarrollo a mediano y largo plazo en la industria farmacológica. spa
dc.description.abstractenglishCurrently, a significant percentage of medicines derived from compounds isolated from living organisms. Considering this perspective, the exploration of new bioactive compounds is inclined to those organisms that have remained unexplored, as occurs with some species of marine algae. This work aimed to phytochemically characterize and identify the applications and benefits from the secondary metabolites of the Caulerpa genus. To conduct this study, an exploratory review of scientific articles was carried out using a systematic approach on databases including Scopus, Pubmed, Marine Drugs, Scielo and Lilacs. The collected information was analyzed using Microsoft Excel® and the reference management software Zotero®. Through the review of 93 scientific articles, the bioprospective potential of biologically active compounds associated with Caulerpa spp. And their impact on the pharmaceutical industry was identified. The findings highlight the compositional and functional importance of sulfated polysaccharides, as well as the secondar y metabolites Caulerpin and Caulerpenyne, along with the fatty acids and extracts of Caulerpa, since these compounds have demonstrated diverse biological activities, including anti-inflammatory, antitumoral, antimicrobial and antioxidant potentials. The presence of Caulerpa spp in the Colombian Caribbean, supported by data on algal diversity at the national level, suggests a significant potential for underexplored resources from Caulerpa in Colombia. These resources hold promise for medium and long-term development in the pharmaceutical industry.spa
dc.description.sponsorshipUniversidad Libre Seccional Barranquilla -- Facultad de Ciencias Exactas y Naturales -- Programa de Microbiologíaspa
dc.formatPDFspa
dc.identifier.urihttps://hdl.handle.net/10901/31396
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dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.coarhttp://purl.org/coar/access_right/c_abf2spa
dc.rights.licenseAtribución-NoComercial-SinDerivadas 2.5 Colombiaspa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.5/co/spa
dc.subjectCaulerpaspa
dc.subjectFitoquímicosspa
dc.subjectMetabolitos secundariosspa
dc.subjectActividad biológicaspa
dc.subjectBioprospecciónspa
dc.subject.lembBiotecnología marinaspa
dc.subject.lembAlgas marinasspa
dc.subject.lembIndustria farmacéuticaspa
dc.subject.lembBúsqueda bibliográficaspa
dc.subject.subjectenglishCaulerpaspa
dc.subject.subjectenglishPhytochemicalspa
dc.subject.subjectenglishSecondary metabolitesspa
dc.subject.subjectenglishBiological activityspa
dc.subject.subjectenglishBioprospectionspa
dc.titleRevisión exploratoria de la composición fitoquímica y las actividades biológicas asociadas de varias especies del género caulerpa y su potencial en la industria farmacéuticaspa
dc.type.coarhttp://purl.org/coar/resource_type/c_7a1fspa
dc.type.driverinfo:eu-repo/semantics/bachelorThesisspa
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersionspa
dc.type.localTesis de Pregradospa

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