Caracterización clínica y endoscópica de pacientes con hemorragia digestiva alta atendidos en el servicio de urgencias de una institución de alta complejidad en Barranquilla 2021-2022
| dc.contributor.advisor | Moscote Granadillo, Mario Joaquín | |
| dc.contributor.advisor | Varela Prieto, Lourdes | |
| dc.contributor.author | Restrepo Marín, Juan David | |
| dc.contributor.author | Valiente Méndez, Ricardo Jesús | |
| dc.coverage.spatial | Barranquilla | spa |
| dc.creator.email | juancho9224@hotmail.com | spa |
| dc.creator.email | ricardojvalientem@ unilibre.edu.co | spa |
| dc.date.accessioned | 2024-02-09T15:55:51Z | |
| dc.date.available | 2024-02-09T15:55:51Z | |
| dc.date.created | 2023 | |
| dc.description.abstract | La hemorragia digestiva alta (HDA) definida como el sangrado procedente desde el esófago hasta el ligamento de Treitz. Es la emergencia gastroenterológica más común en todo el mundo y es de alto impacto en la población por la elevada morbimortalidad, causada por el aumento de consumo de antinflamatorios no esteroideos y la alta prevalencia de Helicobacter pylori representan las principales causas de hemorragias por úlcera péptica. En la revista mundial de gastroenterología se presentan la HDA como una urgencia, con una mortalidad del 6%-13% con una tasa de incidencia de 48 a 160 casos por 100.000 habitantes, reportes consistentes de mayor incidencia entre los hombres y las personas mayores. Las estrategias de gestión han cambiado drásticamente en las últimas décadas debido a la introducción de la terapia de supresión de ácido y la terapia endoscópica la cual se ha convertido en el pilar para el diagnóstico y tratamiento de la HDA. Se plateó un estudio descriptivo, retrospectivo diseñado bajo paradigma cuantitativo, con el objetivo de caracterizar clínica y endoscópicamente a la población con diagnóstico de hemorragia digestiva alta, atendidos en el servicio de urgencias de una institución de alta complejidad en Barranquilla en el periodo 2021 a 2022. Se concluyó que el hallazgo endoscópico de mayor frecuencia fue la ulcera gástrica con el 44.2%, seguido de la gastropatía erosiva 18.3%, ulcera duodenal 15.4%, esofagitis erosiva 7.7%, varices esofágicas 7.2% Mallory Weiss 3.8% y otros hallazgos 3.4%. Se realizó hemostasia endoscópica en el 51.9% utilizándose en su mayoría hemostasia endoscópica dual. | spa |
| dc.description.abstractenglish | Upper gastrointestinal bleeding (UGH) is defined as bleeding from the esophagus to the Treitz ligament. It is the most common gastroenterology emergency worldwide and has a high impact on the population due to the high morbidity and mortality caused by the increased consumption of non-steroidal anti-inflammatory drugs (NSAIDs) and the high prevalence of Helicobacter pylori, which represent the main causes of bleeding from peptic ulcer. In the world journal of gastroenterology, HDA is presented as an emergency with a mortality of 6%-13% with an incidence rate of 48 to 160 cases per 100,000 inhabitants, with consistent reports of higher incidence among men and the elderly. Management strategies have changed dramatically in recent decades due to the introduction of acid suppression therapy and endoscopic therapy which has become become the mainstay for the diagnosis and treatment of HDA. Descriptive, retrospective study designed under the quantitative paradigm was proposed, with the objective of clinically and endoscopically characterizing the population diagnosed with upper gastrointestinal bleeding, treated in the emergency department of a high complexity institution in Barranquilla in the period 2021 to 2021. 2022. It was concluded that the most frequent endoscopic finding was gastric ulcer with 44.2%, followed by erosive gastropathy 18.3%, duodenal ulcer 15.4%, erosive esophagitis 7.7%, esophageal varices 7.2% Mallory Weiss 3.8% and other findings 3.4%. Endoscopic hemostasis was performed in 51.9%, mostly using dual endoscopic hemostasis. | spa |
| dc.description.sponsorship | Universidad Libre Seccional Barranquilla -- Facultad de Ciencias de la Salud -- Especialización en Medicina Interna | spa |
| dc.format | spa | |
| dc.identifier.uri | https://hdl.handle.net/10901/28395 | |
| dc.relation.references | Wilkins T, Khan N, Nabh A, Schade R. Diagnosis and management of upper gastrointestinal bleeding. Am Fam Physician. 2012; 85:469-76 | spa |
| dc.relation.references | Holster I, Kuipers E. Management of acute nonvariceal upper gastrointestinal bleeding: current policies and future perspectives. World J Gastroenterol. 2012; 18:1202–207 | spa |
| dc.relation.references | Astocóndor Villar RE. Características clínicas y endoscópicas de la Hemorragia digestiva alta en el hospital nacional Arzobispo loayza durante el 2017. [Tesis]. Lima, Peru: Universidad Nacional Federico Villarreal; 2018.66p. Disponible en: http://repositorio.unfv.edu.pe/handle/UNFV/1686 | spa |
| dc.relation.references | Wuerth BA, Rockey DC. Changing epidemiology of upper gastrointestinal hemorrhage in the last decade: a national wide analysis. Dig Dis Sci. 2018;63(5):1286-93. doi: 10.1007/s10620-017-4882-6 | spa |
| dc.relation.references | Esrailian E, Gralnek IM. Nonvariceal upper gastrointestinal bleeding: epidemiology and diagnosis: Gastroenterol Clin North Am. 2005;34(4):589-605 | spa |
| dc.relation.references | Laine L, Yang H, Chang SC, Datto C. Trends for incidence of hospitalization and death due to GI complications in the United States from 2001 to 2009. Am J Gastroenterol. 2012;107(8):1190-5; quiz 1196. doi: 10.1038/ ajg.2012.168 | spa |
| dc.relation.references | Cai JX, Saltzman JR. Initial assessment, risk stratification and early management of acute nonvariceal upper gastrointestinal bleeding. Gastrointest Endosc Clin N Am. 2018;28(3):261-75. doi: 10.1016/j.giec.2018.02.001 | spa |
| dc.relation.references | Leontiadis GL, Molloy-Bland M, Moayyedi P, Howden CW. Effect of comorbidity on mortality in patients with peptic ulcer bleeding: systematic review and meta-analysis. Am J Gastroenterol. 2013;108(3):331-45; quiz 346. doi: 10.1038/ajg.2012.451 | spa |
| dc.relation.references | Lanas A, Dumonceau JM, Hunt RH, Fujishiro M, Scheiman JM, Gralnex IM, et al. Nonvariceal upper gastrointestinal bleeding. Nat Rev Dis Prim. 2018; 4:18020. doi: 10.1038/ nrdp.2018.20 | spa |
| dc.relation.references | Charpignon C, Lesgourgues B, Pariente A, Nahon S, Pelauier A, Gatineau-Sailliant G, et al. Peptic ulcer disease: one in five is related to neither Helicobacter pylori nor aspirin/NSAID intake. Aliment Pharmacol Ther. 2013;38(8):946-54. doi: 10.1111/apt.12465 | spa |
| dc.relation.references | Huang JQ, Sridhar S, Hunt RH. Role of Helicobacter pylori infection and non-steroidal anti-inflammatory drugs in peptic-ulcer disease: a meta-analysis. Lancet. 2002;359(9300):14- 22 | spa |
| dc.relation.references | Robles Y, Rodríguez Y, Solara J, Pérez A, Benítez Y. Caracterización de pacientes atendidos por hemorragia digestiva alta. Correo Científico Médico de Holguín (CCM). 2019:23(3);1-14 | spa |
| dc.relation.references | Herrlinger K. [Classification and management of upper gastrointestinal bleeding]. Internist (Berl). 2010; 51:1145-56 | spa |
| dc.relation.references | Rivera H Daysi, Martínez M Julián David, Tovar C José Rafael, Garzón O Martín Alonso, Hormaza A Natan, Lizarazo Jorge I et al. Caracterización de los pacientes con hemorragia de vías digestivas altas no varicosa en un hospital de tercer nivel de Cundinamarca, Colombia. Rev Col Gastroenterol. 2013; 28( 4 ): 278-285. Disponible en: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0120- 99572013000400002&lng=en | spa |
| dc.relation.references | Kumar NL, Nayor J, Saltzman JR. Initial management of nonvariceal upper gastrointestinal bleeding and timing of endoscopy. Techn Gastrointest Endosc. 2016;18(4):170-6. doi.org/10.1016/j.tgie.2016.11.001 | spa |
| dc.relation.references | Ghasssemi KA, Jensen DM. Evolving techniques for gastrointestinal endoscopic hemostasis treatment. Exp Rev Gastroenterol Hepatol. 2016;10(5):615-23. doi: 10.1586/17474124.2016.1130623 | spa |
| dc.relation.references | Laine L. Upper gastrointestinal bleeding due to a peptic ulcer. N Engl J Med. 2016;375(12):1198. doi: 10.1056/ NEJMc1609017 | spa |
| dc.relation.references | Nable J & Graham A. “Gastrointestinal Bleeding.” Emergency Medicine Clinics of North America. 2016; 34, 309–25 | spa |
| dc.relation.references | Sreedharan A, Martin J, Leontiadis GI, Dorward S, Howden CW, Forman D, et al. Proton pump inhibitor treatment initiated prior to endoscope diagnosis in upper 38 gastrointestinal bleeding. Cochrane Database Syst Rev. 2010;(7):CD005415. doi: 10.1002/14651858.CD005415. pub3 | spa |
| dc.relation.references | Sung JJ, Chiu PC, Chan FKL, Lau JY, Goh KL, Ho LH, et al. Asia-Pacific working group consensus on non-variceal upper gastrointestinal bleeding: an update 2018. Gut. 2018. pii: gutjnl-2018-316276. doi: 10.1136/gutjnl-2018-316276 | spa |
| dc.relation.references | Barkun AN, Bardou M, Kuipers EJ, Sung J, Hunt RH, Martel M, et al. International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding. Ann Intern Med. 2010;152(2):101-13. doi: 10.7326/0003-4819-152- 2-201001190-00009 | spa |
| dc.relation.references | Gralnek IM, Dumonceau JM, Kuipers EJ, Lanas A, Sanders DS, Kurien M, et al. Diagnosis and management of nonvariceal upper gastrointestinal hemorrhage: European Society of Gastrointestinal Endoscopy (ESGE) Guideline. Endoscopy. 2015;47(10):a1-46. doi: 10.1055/s-0034-1393172 | spa |
| dc.relation.references | Laine L, Jensen D. Management of patients with peptic ulcer bleeding. Am J Gastroenterol. 2012;107(3):345-60; quiz 361. doi: 10.1038/ajg.2011.480 | spa |
| dc.relation.references | García-Iglesias P, Botargues JM, Caballé FF, VillanuevaSánchez C, Calvet X, Benedi EB, et al. Manejo de la hemorragia digestiva alta no varicosa: documento de posicionamiento de la Societat Catalana de Digestologia. Gastroenterol Hepatol. 2018;40(5):363-74. doi: 10.1016/j. gastrohep.2016.11.009 | spa |
| dc.relation.references | Fortinsky KJ, Bardou M, Barkun AN. Role of Medical Therapy for Nonvariceal Upper Gastrointestinal Bleeding. Gastrointest Endosc Clin N Am. 2015;25(3):463-78. doi: 10.1016/j.giec.2015.02.003 | spa |
| dc.relation.references | Jeong N, Kim KS, Jung YS, Kim T, Shin SM. Delayed endoscopy is associated with increased mortality in upper gastrointestinal hemorrhage. Am J Emerg Med. 2018. pii: S0735- 6757(18)30430-3. doi: 10.1016/j.ajem.2018.05.049 | spa |
| dc.relation.references | Shih PC, Liu SJ, Li ST, Chiu AC, Wang PC, Liu LY. Weekend effect in upper gastrointestinal bleeding: a systematic review and meta-analysis. PeerJ; 2018;6:e4248. doi: 10.7717/ peerj.4248 | spa |
| dc.relation.references | Ghasssemi KA, Jensen DM. Evolving techniques for gastrointestinal endoscopic hemostasis treatment. Exp Rev Gastroenterol Hepatol. 2016;10(5):615-23. doi: 10.1586/17474124.2016.1130623 | spa |
| dc.relation.references | Martínez-Alcalá A, Mönkemüller K. Emerging endoscopic treatments for nonvariceal upper gastrointestinal hemorrhage. Gastrointest Endosc Clin N Am. 2018;28(3):307-20. doi: 10.1016/j.giec.2018.02.004 | spa |
| dc.relation.references | Jensen DM, Kovacs TOG, Ohning GV, Ghassemi K, Machicado GA, Dulai GS, et al. Doppler Endoscopic Probe Monitoring of Blood Flow Improves Risk Stratification and Outcomes of Patients With Severe Nonvariceal Upper Gastrointestinal Hemorrhage. Gastroenterology. 2017;152(6):1310-18. doi: 10.1053/j.gastro.2017.01.042 | spa |
| dc.relation.references | Neumann I, Letelier LM, Rada G, Claro JC, Martin J, Howden CW, et al. Comparison of different regimens of proton pump inhibitors for acute peptic ulcer bleeding. Cochrane Database Syst Rev. 2013;(6):CD007999. doi: 10.1002/14651858.CD007999.pub2 | spa |
| dc.relation.references | Gisbert JP, Khorrami S, Carballo F, Calvet X, Gene E, Dominguez-Muñoz E. Metaanalysis: Helicobacter pylori eradication therapy vs. antisecretory non-eradication therapy for the prevention of recurrent bleeding from peptic ulcer. Aliment Pharmacol Ther. 2004;19(6):617-29 | spa |
| dc.relation.references | Otero W, Gómez M, Otero PL, Trespalacios AA. Helicobacter pylori: ¿cómo se trata en el 2018? Rev Gastroenterol Perú. 2018;38(1):54-63 | spa |
| dc.rights.accessrights | info:eu-repo/semantics/openAccess | spa |
| dc.subject | Úlcera péptica | spa |
| dc.subject | Úlcera duodenal | spa |
| dc.subject | Hemostasis endoscópica | spa |
| dc.subject | Colombia – DeCS | spa |
| dc.subject.lemb | Úlcera duodenal | spa |
| dc.subject.lemb | Úlcera péptica | spa |
| dc.subject.lemb | Hemorragia gastrointestinal | spa |
| dc.subject.subjectenglish | Peptic ulcer | spa |
| dc.subject.subjectenglish | Duodenal ulcer | spa |
| dc.subject.subjectenglish | Hemostasis endoscopic | spa |
| dc.subject.subjectenglish | Colombia – DeCS | spa |
| dc.title | Caracterización clínica y endoscópica de pacientes con hemorragia digestiva alta atendidos en el servicio de urgencias de una institución de alta complejidad en Barranquilla 2021-2022 | spa |
| dc.type.driver | info:eu-repo/semantics/bachelorThesis | spa |
| dc.type.local | Tesis de Especialización | spa |
Archivos
Bloque original
1 - 2 de 2
Cargando...
- Nombre:
- FORMULARIO AUTORIZACION.pdf
- Tamaño:
- 1.42 MB
- Formato:
- Adobe Portable Document Format
- Descripción:
- Autorización para la publicación
Cargando...
- Nombre:
- RESTREPO.pdf
- Tamaño:
- 573.01 KB
- Formato:
- Adobe Portable Document Format
- Descripción:
- Archivo del trabajo para descargar
Bloque de licencias
1 - 1 de 1
Cargando...
- Nombre:
- license.txt
- Tamaño:
- 1.71 KB
- Formato:
- Item-specific license agreed upon to submission
- Descripción: