Desenlaces materno-perinatales en pacientes con Diabetes Gestacional en manejo con insulina análogas vs insulinas humanas en instituciones de salud de la ciudad de Barranquilla, 2022 – 2024

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dc.contributor.advisorPrasca De la Hoz, Richard
dc.contributor.advisorGarcía, Aracely
dc.contributor.authorHernández Fernández de Castro, Tania
dc.contributor.authorSuárez Henríquez, María De Los Ángeles
dc.coverage.spatialBarranquillaspa
dc.creator.emailtaniahernandezfdc@gmail.comspa
dc.creator.emailmariad-suarezh@unilibre.edu.cospa
dc.date.accessioned2025-07-18T14:34:32Z
dc.date.available2025-07-18T14:34:32Z
dc.date.created2025-06-20
dc.description.abstractIntroducción: La diabetes gestacional (DG) es una complicación frecuente en el embarazo, asociada a riesgos maternos y perinatales. El tipo de insulina utilizada para su control puede influir en los desenlaces, pero la evidencia en contextos locales es limitada. Objetivo: Comparar los desenlaces materno-perinatales en gestantes con diabetes gestacional tratadas con insulinas análogas versus insulinas humanas en instituciones de salud de Barranquilla entre 2022 y 2024. Metodología: Se realizó un estudio analítico, observacional y retrospectivo, tipo casos y controles, incluyendo 134 gestantes con diagnóstico de DG según criterios IADPSG. Se evaluaron variables sociodemográficas, obstétricas y características del tratamiento, comparando complicaciones maternas y perinatales entre ambos grupos. Resultados: El ingreso a unidad de cuidado intensivo neonatal fue la complicación perinatal más frecuente (50,7%), mientras que la preeclampsia severa predominó entre las maternas (19,5%). No se encontró asociación estadísticamente significativa entre el tipo de insulina y la presencia de complicaciones (p=0,299). Sin embargo, sí hubo diferencias significativas en índice de masa corporal, peso materno y edad gestacional al inicio del tratamiento y al parto entre los grupos. Discusión y conclusión: Los resultados sugieren que el uso de insulinas humanas o análogas no afecta significativamente los desenlaces materno-perinatales adversos. Otros factores maternos y obstétricos podrían tener mayor impacto en las complicaciones observadas. Estos hallazgos aportan información útil para optimizar el manejo clínico de la DG en contextos locales.spa
dc.description.abstractenglishBackground: Gestational diabetes (GD) is a common pregnancy complication associated with maternal and perinatal risks. The type of insulin used for its management may influence outcomes, but evidence in local settings is limited. Objective: To compare maternal and perinatal outcomes in pregnant women with gestational diabetes treated with analog insulins versus human insulins in health institutions of Barranquilla between 2022 and 2024. Methodology: An analytical, observational, retrospective case-control study was conducted including 134 pregnant women diagnosed with GD according to IADPSG criteria. Sociodemographic, obstetric, and treatment characteristics were evaluated, comparing maternal and perinatal complications between groups. Results: Admission to the neonatal intensive care unit was the most frequent perinatal complication (50.7%), while severe preeclampsia was the most common maternal complication (19.5%). No statistically significant association was found between insulin type and presence of complications (p=0.299). However, significant differences were observed in body mass index, maternal weight, and gestational age at treatment initiation and delivery between groups. Discussion and Conclusion: Results suggest that the use of human or analog insulins does not significantly affect adverse maternal and perinatal outcomes. Other maternal and obstetric factors may have greater impact on observed complications. These findings provide useful information for optimizing clinical management of GD in local contexts.spa
dc.description.sponsorshipUniversidad Libre - Facultad de Ciencias de la Salud - Especialización en Ginecología y Obstetriciaspa
dc.formatPDFspa
dc.identifier.urihttps://hdl.handle.net/10901/31531
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dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.coarhttp://purl.org/coar/access_right/c_abf2spa
dc.rights.licenseAtribución-NoComercial-SinDerivadas 2.5 Colombiaspa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.5/co/spa
dc.subjectDiabetes gestacionalspa
dc.subjectInsulina análogaspa
dc.subjectInsulina humanaspa
dc.subjectComplicaciones maternasspa
dc.subjectDesenlaces perinatalesspa
dc.subject.lembDesenlaces maternos - perinatales en pacientes con diabetes gestacional en manejo con insulina análogas vs insulinas Humanas en Instituciones de salud de la ciudad de Barranquillaspa
dc.subject.subjectenglishGestational diabetesspa
dc.subject.subjectenglishAnalog insulinspa
dc.subject.subjectenglishHuman insulinspa
dc.subject.subjectenglishMaternal complicationsspa
dc.subject.subjectenglishPerinatal outcomesspa
dc.titleDesenlaces materno-perinatales en pacientes con Diabetes Gestacional en manejo con insulina análogas vs insulinas humanas en instituciones de salud de la ciudad de Barranquilla, 2022 – 2024spa
dc.type.coarhttp://purl.org/coar/resource_type/c_7a1fspa
dc.type.driverinfo:eu-repo/semantics/bachelorThesisspa
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersionspa
dc.type.localTesis de Especializaciónspa

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